RECENT PUBLICATIONS

  1. Su, Y-P, et al. Characterization of integrated hepatitis B virus DNA harboring pre-S mutations in hepatocellular carcinoma patients with ground glass hepatocytes. J Med Virol. 2024 Jan; 96(1):e29348. DOI: 10.1002/jmv.29348. (2024)
  2. Kim, A.K., Hamilton, J.P., Lin, S.Y., et al. Urine DNA biomarkers for hepatocellular carcinoma screening. British J of Cancer (2022)
  3. Lin, S.Y., Su, Y-P, Trauger, E.R., et al. Detection of Hepatitis B Virus–Host Junction Sequences in Urine of Infected Patients. Hepatology Communications. DOI: 10.1002/hep4.1783 (2021)
  4. Lin, S.Y., Zhang, A., Lian, J. et al. Recurrent HBV Integration Targets as Potential Drivers in Hepatocellular Carcinoma. Cells 2021, 10(6), 1294. DOI: 10.3390/cells10061294 (2021)
  5. Lin, S.Y., Chang, T-T, Steffen, J.D. et al. Detection of CTNNB1 Hotspot Mutations in Cell-Free DNA from the Urine of Hepatocellular Carcinoma Patients. Diagnostics 2021, 11(8), 1475. DOI: 10.3390/diagnostics11081475 (2021)
  6. Lin, S.Y., Luo, Y., Marshall, M.M. et al. A New Method for Improving Extraction Efficiency and Purity of Urine and Plasma Cell-Free DNA. Diagnostics 2021, 11(4), 650. DOI: 10.3390/diagnostics11040650 (2021)
  7. S. Jain., Chang, T-T., Chen, S., Lin, S. Y., Boldbaatar B, Hamilton J.P., Chen S-H, Hu C-T., Meltzer S.J., Block T.M., Song, W., and Su, Y-H. Comprehensive DNA methylation analysis of hepatitis B virus genome in infected liver tissues. Scientific Report 5:10478 | DOI: 10.1038/srep10478 (2015)
  8. S. Jain, Xie, L., Chen, S., Lin, S. Y., Boldbaatar, B., Hamilton,J.P., Chen S-H, Hu, C-T, Meltze,r S.J., Block, T.M., Su, Y-H, Song, W. Differential CpG methylation within the RASSF1A gene as a biomarker for liver cancer screening. Hepatology Research, DOI: 10.1111/hepr.12449 (2014)
  9. Y-H Su, Lin, S.Y., Song, W., and Jain, S. DNA markers in molecular diagnostics for hepatocellular carcinoma. Expert Review of Molecular Diagnostics 14(7), 803-817 (2014)
  10. S.Jain, Wojdacz, TK and Su, Y-H. Challenges for the application of DNA methylation biomarkers in molecular diagnostic testing for cancer. Expert Review of Molecular Diagnostics 13 (3), 283-294 (2013)
  11. B. P. Song, S. Jain, S. Y. Lin, Q. Chen, W. Song, T. M. Block, D. E. Brenner, and Y-H Su. Detection of hypermethylated vimentin in urine of patients with colorectal cancer. J of Molecular Diagnostic, 14 (2): 112-119.
  12. Jain S., Chen S., Boldbaatar B., Hu C-T, Hamilton J.P., Lin S.Y., Chang T-T, Chang K-C, Chen S-H, Song W., Meltzer S.J., Block T.M. and Su Y-H. Impact of the Location of CpG methylation within the GSTP-1 Gene on Its Specificity as a DNA Marker for Hepatocellular Carcinoma. PLoS ONE 7(4): e35789. doi:10.1371 (2012)
  13. S. Y. Lin, S. Jain, L. Yu, S-H Chen, W. Song, T. M. Block, and Y-H Su. Development of an assay for detection of HBV 1762T/1764A double mutation in urine of patients with HBV-associated hepatocellular carcinomas. InTech chapter “Hepatocellular Carcinoma-Clinical Research” p139-154, (2012)
  14. S. Jain, T-T Chang, J. P. Hamilton, S. Y. Lin, S. Chen, Y-J Lin, A. A. Evans, F. M. Selaru, P-W Lin, S-H Chen, W. Song, T M. Block, S. J. Meltzer, Y-H Su Only Methylation of the CpG Sites on the Sense Strand of the APC Gene is Specific for Hepatocellular Carcinoma PLoS One 6: e26799 (2011)
  15. S. Y. Lin, V. Dhillon, S. Jain, T-T Chang, C-T Hu, Y-J Lin, S-H Chen, W. Song, L. Yu, T. M. Block, and Y-H Su. A Locked Nucleic Acid Clamp-Mediated Polymerase Chain Reaction Assay for Detection of a P53 Codon 249 Hotspot Mutation in Urine. J of Molecular Diagnostic, 13: 474-484 (2011)
  16. L. Kleinberg, P. J. Catalano, M. K. Gibson, C. A. Staley, E. Montgomery, W. Song, M. F. Mulcahy, L. P. Leichman, A. B. Benson. ECOG 2205: A Phase II Study to Measure Response Rate and Toxicity of Neo-adjuvant Chemoradiotherapy (CRT) (IMRT permitted) with Oxaliplatin (O) and Infusional 5-Fluorouracil (5FU) Plus Cetuximab (C225) in Patients with Operable Adenocarcinoma of the Esophagus: High Risk of Post-op Adult Respiratory Distress Syndrome (ARDS), presented at 52nd ASTRO Annual Meeting; San Diego, CA, International Journal of Radiation Oncology, Vol 78, issue 3, Supplement, Page S72, November, 2010.
  17. M. K. Gibson, P. J. Catalano, L. Kleinberg, C. A. Staley, E. Montgomery, W. Song, M. F. Mulcahy, L. P. Leichman, A. B. Benson. E2205: A phase II study to measure response rate and toxicity of neoadjuvant chemoradiotherapy (CRT) with oxaliplatin (OX) and infusional 5-fluorouracil (5-FU) plus cetuximab (C) followed by postoperative docetaxel (DT) and C in patients with operable adenocarcinoma of the esophagus. 2010 ASCO Annual Meeting, Chicago, IL. Journal of Clinical Oncology, 2010 ASCO Annual Meeting Proceedings (Post-Meeting Edition). Vol 28, No 15_suppl (May 20 Supplement), 2010: 4064
  18. Y-H Su, M. Wang, P. A. Norton, D. E. Brenner, and T. M. Block. Incidence of detecting mutated k-ras DNA in urine, plasma and serum from patients with carcinoma or adenomatous polyps. Ann. N. Y. Acad. Sci. 1137 (1): 197-206 (2008)
  19. Y-H Su, J. Song, Z. Wang, X. Wang, M. Wang, D. E. Brenner, and T. M. Block. Removal of high molecular weight DNA by carboxylated magnetic beads enhances the detection of mutated K-ras DNA in urine. Ann. N. Y. Acad. Sci. 1137 (1): 82-91 (2008)
  20. Y-H Su, M. Wang, B. Aiamkitsumrit, D. E. Brenner, and T.M. Block. Detection of K-ras mutation in urine of patients with colorectal cancer. Cancer Biomarkers 1, 177-182. (2005)
  21. Y-H Su, M. Wang, D. E. Brenner, A. Ng, H. Melkonyan, S. Umansky, S. Syngal, and T. M. Block. Human urine contains small, 150-250 nucleotide sized, soluble DNA derived from the circulation and may be useful in the detection of colorectal cancer. Journal of Molecular Diagnostics 6, 101-107. (2004).
  22. Y-H Su, M. Wang, T. M. Block, O. Landt, I. Botezatu, O. Serdyuk, A. Lichtenstein, H. Melkonyan, L. D. Tomei, S.l Umansky. Transrenal DNA as a diagnostic tool: important technical notes. Ann. N. Y. Acad. Sci. 1002: 81-89 (2004).
  23. Cao, L., and Song, W. 1999. Coronary artery disease in men and women. N Engl. J Med. 341:1932-1933(letter).